Clipping cancer with CRISPR

Preserving Sharp Edges with Volume Clipping

Volume clipping is a useful aid for exploring volumetric datasets. To maximize the effectiveness of this technique, the clipping geometry should be flexibly specified and the resulting images should not contain artifacts due to the clipping techniques. We present an improvement to an existing illumination model for volume clipping to allow sharp edges in the data to stay visible. These sharp ed...

Clipping along.

In this issue of JMB, Rajendar and Lucius report a study of themechanism of polypeptide translocation catalyzed by the Escherichia coli ClpA enzyme—the motor component of the ATP-dependent protease, ClpAP. ATP-dependent proteases play important roles in protein turnover and share a common architecture across organisms. ClpAP is composed of the hexameric AAA+ motor protein ClpA and the tetradeca...

Predicting Word Clipping with Latent Semantic Analysis

In this paper, we compare a resourcedriven approach with a task-specific classification model for a new near-synonym word choice sub-task, predicting whether a full or a clipped form of a word will be used (e.g. doctor or doc) in a given context. Our results indicate that the resourcedriven approach, the use of a formality lexicon, can provide competitive performance, with the parameters of the...

Low Proteolytic Clipping of Histone H3 in Cervical Cancer

Chromatin in cervical cancer (CC) undergoes chemical and structural changes that alter the expression pattern of genes. Recently, a potential mechanism, which regulates gene expression at transcriptional levels is the proteolytic clipping of histone H3. However, until now this process in CC has not been reported. Using HeLa cells as a model of CC and human samples from patients with CC, we iden...

Clipping Wings